The 2 Channel Synthesis System (B) enables pressurised flow reactions with 2 independently controlled substrate/reagent inputs and two reaction locations with independent temperature control.
The 2 Channel Synthesis System (B) is ideal for use in the following applications:
* Medicinal chemistry
o Flow chemistry investigations
o Intermediate production
o Synthetic conditions not possible in regular batch chemistry
* Process chemistry
o Reaction optimisation (manual collections)
o Early scale-up
* Degradation testing
* Stability studies
2 Syringe Pumps:
Flow rate 2.5µl to 2.5ml/min with pressure sensors and automatic over-pressure shutdown
4 Pressurized Input Bottles:
Regulated 1 bar Nitrogen or Argon is supplied to up to 4 bottles, eliminating cavitation and bubble formation and allowing the use of air sensitive reagents (requires laboratory gas supply).
4 Manual Injection Loops and Valves:
1ml, 5ml or 10ml loops
All wetted parts are glass, PTFE or other similar fluoropolymer.
2 Temperature Controlled Microreactor Positions:
The Africa Heater/Cooler has two reaction positions, each of which can be factory set to either:
* 0°C – 150°C
* 40°C – 250°C
Automated Product Collection:
Each different reaction is automatically collected in a different vial. The vial (or vessel) size is set by the user. Reactions larger than the vial size are automatically collected across multiple vials or preparative quantities can be collected in large one vessel.
The Africa software allows an almost unlimited number of reactor configurations and automates the entire process. Only “chemist friendly” data such as volumes, times and temperatures need to be added – no need to deal with flow rates if you don’t want to. The timings of all events such as pumps starting, collections etc. are all automatically calculated.
The 2 Channel Synthesis (B) System contains the following modules:
Description Part Number
Microreactors - Various
Tube Reactors - Various
Reagent Pumps - 2100140
Heater/Cooler - 2100090
Reagent Store - 2100150
Pressurisation Module - 2110701
Tube Reactor Heater (Optional) - 2100640
Laptop and Software - 2110724
Synthesis Pack - 2110714